JDRF is the world’s largest nonprofit funder of type 1 diabetes (T1D) research. Our focus is on finding a cure; until we do, the advancements we’re making every day improve the lives of those living with the disease until that day comes.

Closing in on Cures

We don’t yet know where the cures will come from, but we have identified several paths that have the most promise. We invest in these projects at the earliest stages and continue to fund those that deliver results across the therapy development pipeline, ensuring the most innovative ideas and approaches turn into breakthrough treatments. Today, several of those ideas and approaches are in human clinical trials.
Explore our research portfolio below.

Our Strategy: Curing T1D. Improving Lives.

Our research has two core objectives: Cures by restoring the body’s ability to make insulin and stopping T1D before it occurs or providing insulin independence through replacement with insulin producing cells, and Improving Lives by keeping people with T1D as healthy as possible until cures are found by advancing new T1D resources, technologies, and therapies.

JDRF has a plan to achieve our mission and vision of a world without T1D. Guided by our two pillars, Cures and Improving Lives, JDRF has a 5 year plan to bring us closer to Cures for T1D. This plan, created by JDRF scientists and approved by our International Board of Directors, most of whom have a direct T1D connection, focuses JDRF’s resources on the key drivers that will have the biggest impact on achieving our goals.
Learn more about our research strategy here.


We don’t have cures for T1D yet, but we know what must be done to make them a reality. To find cures for T1D, we need to:

  • Restore or replace insulin production

  • Turn off the autoimmune attack responsible for destroying the beta cells

To achieve this, JDRF’s Cures portfolio is focused on three areas:

Improving Lives

People with T1D must have tools, therapies, and interventions to keep them healthy so that when cures come to fruition, they are healthy enough to take advantage of them. To achieve this, JDRF’s Improving Lives portfolio is focused on two areas:

Investing in the Future

In order to cure T1D and improve lives, the T1D field must continue to attract the top minds. That’s why JDRF will continue to foster a healthy community of T1D researchers by supporting training awards and fellowships, and bridging the gap between endocrinologists, transplant surgeons, psychologists, and immunologists.

Meet our Grantees Here

Want to learn more? Watch JDRF Vice President, Research talk through JDRF’s research portfolio. You can also see him go over the top advances of FY21 here.