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Complications

Despite advances that are giving people with type 1 diabetes (T1D) better tools to control their disease, those living with T1D are still at risk of developing serious health problems such as kidney, eye, heart and nerve diseases. The JDRF Complications Program focuses on diabetic kidney and eye diseases, two areas where we believe we have the best opportunity to make short- and long-term impact on people’s lives.

Our Approach

Research shows rigorous insulin therapy could significantly reduce the risk of diabetes complications. Only one-third of people with T1D, however, are currently achieving the recommended blood-sugar targets.

  • Discover biomarkers

    to enable clinical trials targeting the early stages of disease

  • Identify genes

    so people with the greatest risk can take steps to intervene early

  • Include people with T1D in type 2 diabetes clinical trials

    so that promising treatments extend to T1D

“I learned at a young age the effect T1D could have on my eyes, and while the possibility of vision loss was a very scary thought, it’s not something I expected to encounter at age 34. After my diagnosis of Diabetic Eye Disease and retinopathy, I’m so grateful to have benefitted from the life-changing research being done to introduce new treatment options and reverse the effects of eye-related complications. I look forward to the day when vision loss is one less thing for people living with T1D to worry about.”

Elisabeth W.

35 years old, diagnosed at age 7

Kady T.

Many Paths, One Purpose

Our research into complications stemming from T1D, including vision and kidney disease, is just one potential pathway to finding a cure for T1D. Explore JDRF’s ambitious research portfolio.

All Research

Looking Ahead

To date, more than $115 million has been invested by JDRF in complications research. One day, complications are reversed and prevented for people living with T1D.