Mid Atlantic Chapter

T1D Clinical Trials in the Mid-Atlantic Region

Participate in a T1D Clinical Trial

Choosing to participate in a T1D clinical trial is a very personal decision, but one that can have a significant impact on curing, preventing and treating T1D. Explore additional clinical trial resources from JDRF and our partners at Beyond Type 1 to learn more about clinical trials and their phases.

There are many opportunities in Maryland, Virginia, and Washington, DC to participate in a T1D clinical trial close to home. See below for active opportunities. You can also utilize JDRF’s Clinical Trials Connection tool to find additional opportunities.

If you have any questions, please contact one of our Mid-Atlantic Chapter Clinical Trials Education Volunteers: Tom Brobson or Mike Anderson.


The PROTECT Study will assess how well an investigational medicine, called teplizumab, works in children and adolescents (age 8-17) recently diagnosed (six weeks or less) with T1D. Learn more and find a study clinic here. Local sites include Camp Springs, MD, Philadelphia, PA and Chapel Hill, NC. 


COVID-19 Booster Vaccine Study in People with Type 1 Diabetes
Clinicians from Johns Hopkins are conducting a research study to see if the COVID-19 Booster Vaccine increases glucose levels or insulin requirements in patients with type 1 diabetes.


LOCATION:  Suburban Hospital and Howard County General Hospital Medical Campus


A study to learn about sugar-free foods and beverages for type 1 diabetes management.

PARTICIPANT AGE: 5-14; must have had T1D for at least one year

LOCATION: Requires two in-person visits to Children’s National in Washington, DC and additional virtual meetings


Low Calorie Sweetener and Quality of Life Study
A study to learn about quality of life in youth with type 1 diabetes.

PARTICIPANT AGE: 11-17; must have had T1D for at least one year

LOCATION: Virtual (One 30-minute Zoom meeting and online surveys)


Artificial Pancreas – Adolescent Physiology & Psychology Longitudinal Evaluation (AP APPLE)
The purpose of this study is to find out if teenagers going through puberty with T1D can control their diabetes better by using an artificial pancreas (AP) system as compared to performing their usual diabetes care. The study involves wearing a CGM, blood draws, pubertal assessment, completing questionnaires and possibly wearing a Tandem Control IQ system. The study will require four study visits that last up to one hour and can be done virtually. There are also up to eight study-related phone calls. These visits will last about 15 minutes. Study-related lab tests, study equipment and their associated supplies, are free of charge. Compensation for study completion is $400.


LOCATION: Virtual or by phone or in-person in Charlottesville, VA

CONTACT: APPLE@hscmail.mcc.virginia.edu


Closed Loop Study for Adolescents with Type 1 Diabetes
The purpose of the study is to test a smart bolus calculator that adjusts prandial insulin based on changes in insulin sensitivity throughout the day.  All children will wear study equipment (Dexcom G6 sensor and Tandem t:slim pump) and use a closed loop algorithm during the study. The study will take place at an outdoor camp in Charlottesville, VA


DATES & LOCATION: June 19-24, 2022 at Camp Holiday Trails, Charlottesville, VA

CONTACT: Emma Emory, EE9M@virginia.edu or 434-982-6479 or Lianna Smith, LHS7PX@virginia.edu or 434-284-0893


Adapting Diabetes Treatment Expert Systems to Patient’s Expectations and Psychobehavioral Characteristics in Type 1 Diabetes
The Center for Diabetes Technology seeks adults ages 18 and up with type 1 diabetes for a research study. The purpose of this study is to test different ways CGM data can be used to help manage your diabetes. You may be eligible for this study if you have had type 1 diabetes for at least one year and using insulin for at least one year, and your A1c is between 6.0% – 11%. This study involves using a Dexcom G6 sensors, and an investigational diabetes application on an Android smart phone. Participants currently using multiple daily injections (MDI) may use a study insulin pump, if desired. There will be weekly surveys to complete, as well as 3 separate blood draws for A1c and lab values. This study will last approximately 7 months and there will be approximately 7 visits. All of these visits can be completed virtually using a web-based video conferencing tool. Study-related Dexcom G6 sensors, transmitters, and infusion sets if applicable will be provided free of charge.


LOCATION: Virtual or in-person in Charlottesville, VA

CONTACT: Emma Emory, EE9M@virginia.edu or 434-982-6479


A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
Read more about this clinical trial and its study site at VCU Medical Center in Richmond, VA here.


Are you interested in participating in a clinical trial but these aren’t right for you? Check out JDRF’s Clinical Trial Matching Tool, which can potentially match you with a clinical trial. You can also contact one of our Mid-Atlantic Chapter Clinical Trials Education Volunteers: Tom Brobson or Mike Anderson.

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